Two proven approaches. One combined protocol.
Modern science offers two distinct, independently validated approaches to healing mental and emotional conditions: compound-assisted sessions and structured sound-frequency therapy. Eleusis is among the first research programs in Europe to combine both — deliberately, in a single supervised setting, as one protocol.
Psilocybin and N,N-DMT act on the brain's serotonin 2A receptors, temporarily relaxing rigid patterns of thought and opening a window of heightened neuroplasticity — the brain's ability to rewire itself. That window is where our work happens. All sessions take place inside the institute, under continuous professional supervision.
Psilocybin 4-phosphoryloxy-N,N-DMT
The most extensively studied compound in the modern research literature, with randomized controlled trials in depression, end-of-life anxiety, and alcohol and tobacco dependence — and drug-dependence research now underway.
- Route
- Oral, precisely dosed within the protocol
- Session
- 4–6 hours, two trained facilitators present throughout
- Paradigm
- One to two high-dose sessions within the program
- Status
- Phase 2 clinical trial data published in NEJM and JAMA Psychiatry
N,N-DMT N,N-dimethyltryptamine
A short-acting compound of the same tryptamine family. Its compressed time course makes it uniquely suited to controlled research settings; neuroimaging work has mapped its effects on brain-network activity in detail.
- Route
- On-site sessions under the research protocol
- Session
- Minutes-scale onset; extended-infusion paradigms under study
- Paradigm
- Offered within our dedicated DMT research track
- Status
- Early-phase clinical research; a Phase 2a trial in depression has reported positive results
You come to us. Everything happens here.
Administration takes place in purpose-built session suites inside the institute — a calm, private, medically equipped environment designed for this work and nothing else.
- Physician-led medical and psychiatric screening before acceptance
- Two trained facilitators present for the entire duration
- A luxurious, private venue set in beautiful natural surroundings, with calming landscapes that support the work
- Structured preparation before, and integration after, each session
- Standardized outcome measurement feeding our research dataset
Sound is not background. It is half of the program.
Controlled studies show that exposure to precisely engineered auditory frequencies — binaural and monaural beats, tuned tonal layers — measurably reduces anxiety and pain perception. Music therapy holds a Cochrane-level evidence base in depression. Our tonal palette also includes specific pure tones — among them 528 Hz — for which early human data shows reduced cortisol, increased oxytocin, and lower tension-anxiety scores after even a single brief exposure.
Every administration session pairs the compound with its sound-frequency protocol. The compound opens the neuroplasticity window; the sound frequencies guide attention, emotion, and imagery while that window is open — the role researchers have described as the "hidden therapist" of the session.
This deliberate pairing — two validated approaches, one supervised setting — is what our research program is designed to document, measure, and refine.